To evaluate the changes in corneal topography indices and corneal thickness after cross-linking treatment for
Study Design: Retrospective Observational Study
Patients and Methods: The data of patients who underwent corneal collagen cross-linking treatment for keratoconus were
retrieved. Central corneal thickness (CCT), maximum and mean keratometry (Kmax, Kmean) values and topography indices: index
of surface variance (ISV), index of vertical asymmetry (IVA), keratoconus index (KI), central keratoconus index (CKI), minimum
radius of curvature (Rmin), index of height asymmetry (IHA), and index of height decentration (IHD) were obtained from
Pentacam and Wavelight-Allegretto Wave Topolyzer outputs. Follow-up was 18 months.
Results: The study comprised of 15 eyes of 10 patients with keratoconus. Central corneal thickness had decreased significantly
1 month after the procedure (p=0.003) but there were no statistically significant changes between the baseline values and
last visits (p>0.05). Kmax and Kmean values were not statistically different from the preoperative values and at the last visits
(p>0.05). Almost all of the corneal topography indices improved significantly after postoperative 6th month (p<0.05).
Conclusion: There were improvements in topography indices during 18-month follow-up period, suggesting that the cornea
becomes more optically regular and symmetrical after cross-linking.