Acıbadem Üniversitesi Sağlık Bilimleri Dergisi 2020 , Vol 11, Issue 4
The Diagnostic Value of Complete Blood Test Parameters In Acute Appendicitis: We Should Not Only Take Into Account Wbc
Sönmez Ocak1,Ömer Faruk Bük1,Ahmet Burak Çiftci1
1Department of General Surgery, Samsun Education and Training Hospital, Samsun, Turkey DOI : 10.31067/0.2020.283 Background: Appendectomy is the most common urgent surgical procedure but a diagnosis of acute appendicitis still remains challenging. In this retrospective study, we aimed to evaluate the value of the complete blood count (CBC) test parameters in acute appendicitis.

Materials and methods: Data of 131 patients who underwent appendectomy between January 2016 ? December 2016 were collected retrospectively. Demographic features, CBC parameters and final histopathological results of the patients were recorded. The patients were divided into two groups according to the final pathological results (Group 1: Acute appendicitis group, Group 2: Normal appendices group) and were compared in terms of WBC (white blood cell), platelet count, hemoglobin level, RDW (red cell distribution width), MPV (mean platelet volume) and NLR (neutrophil to lymphocyte ratio) values.

Results: 13 of 131 patients had normal appendices. WBC, platelet and NLR values were signifcantly higher in Group 1 compared to the Group 2 (p<0.001, p<0.017, p<0.001 respectively). MPV value was significantly lower in Group 1 compared to the Group 2 (p<0.041). The cut-off levels for WBC, platelet, MPV and NLR were ?9200 ?L (sensitivity: 84.7%, specificity: 69.2%), ?244500 ?L (sensitivity: 57.6% specificity: 84.6%), ?8.15 fl (sensitivity: 69.2%, specificity: 64.4%) and ?2.795 (sensitivity: 81.4% specificity: 76.9%) respectively.

Conclusion: In addition to WBC, NLR, platelet and MPV levels can be helpful for acute appendicitis diagnosis with no extra costs. Keywords : Appendicitis, red cell distribution width, platelets, neutrophil, lymphocyte