Acıbadem Üniversitesi Sağlık Bilimleri Dergisi 2019 , Vol 10, Issue 2
A Patient Admitted With Diabetic Ketoacidosis and Developing Secondary Hemophagocytic Syndrome
Seher Erdoğan1,Alper Gök2,Ali Bay3,Mehmet Boşnak1
1Gaziantep University, Pediatric Intensive Care Unit, Gaziantep, Turkey
2Gaziantep University Faculty of Medicine, Department of Child Health and Diseases, Gaziantep, Turkey
3Gaziantep University, Department of Pediatric Hematology, Gaziantep, Turkey
DOI : 10.31067/0.2019.157 Hemophagocytic lymphohistiocytosis is characterized by high body temperature, splenomegaly, bicytopenia, hypertriglyceridemia, hyperferritinemia, hypofibrinogenemia, decreased natural killer cell activity, increased soluble CD25 activity and the presence of hemophagocytosis in organs such as the bone marrow, the lymph glands, spleen and liver. We described a patient who was admitted to the intensive care unit with a diagnosis of diabetic ketoacidosis and transferred to the ward when her general condition improved, but who was also diagnosed with hemophagocytic lymphohistiocytosis by bone marrow investigation performed due to a resistant fever, splenomegaly, bicytopenia and hyperferritinemia. Keywords : Hemophagocytic lymphohistiocytosis, Diabetes Mellitus