Acıbadem Üniversitesi Sağlık Bilimleri Dergisi 2020 , Vol 11, Issue 4
The Relationship Between Trace Elements and Complications of Diabetes Mellitus
Mustafa Çağrı Sayılır1,Bülent Erbil2,Mehmet Ali Aslaner3,Mehmet Mahir Özmen4
1Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi, Acil Tıp, Ankara, Türkiye
2Hacettepe Üniversitesi Tıp Fakültesi, Acil Tıp, Ankara, Türkiye
3Gazi Üniversitesi Tıp Fakültesi , Acil Tıp, Ankara, Türkiye
4Liv Hospital, Genel Cerrahi, Ankara, Türkiye
DOI : 10.31067/0.2020.316 Objectives: The effect of trace elements (zinc (Zn), chromium (Cr), selenium (Se), iron (Fe), copper (Cu), vanadium (Va)) on the glucose metabolism is known. The aim of this study was to determine the relationship between trace element levels and acute diabetes mellitus (DM) complications in patients presented to the emergency department (ED).

Patients and Methods: Patients presented to the ED of a university hospital between January and February 2012 over the age of 18 with newly or previously diagnosed DM, were included in the study. The control group was selected from healthy individuals over the age of 18 without any known disease or drug use. Trace element levels were obtained by the atomic absorption spectrophotometric method using the TQ X5 ICP-MS device. Trace element levels were compared between DM and control group as well as between DM complications and control group.

Results: A total of 249 (124 female) patients were included in the study. 151 (84 women) were in the study group and 98 (40 women) in the control group. When the measured trace element levels of the diabetic patients were compared with those of the control group, there was no significant difference in the mean values (p>0.05). There was also no significant difference between patients (n=11) with acute diabetic complications (diabetic ketoacidosis, diabetic ketosis and hyperglycemia) and the control group (p>0.05).

Conclusion: In this study, no significant difference was found between the trace element levels of the diabetic complications group and those of the control group. Keywords : Diabetes Mellitus, trace element, zinc, chromium, selenium, iron, copper, vanadium