Acıbadem Üniversitesi Sağlık Bilimleri Dergisi 2020 , Vol 11, Issue 3
The Relationship of Migraine Clinical Features With Neutrophil- Lymphocyte Ratio
Fatma Şimsek1,Nuray Bilge1,Mustafa Ceylan1
1Atatürk Üniversitesi Tıp Fakültesi, Nöroloji, Erzurum, Türkiye DOI : 10.31067/0.2020.292 Purpose: Migraine is associated with serious social and economic burdens. Migraine attacks are associated with trigeminal nerve stimulation and neurogenic inflammation. It has been reported that the frequency of the attacks and disease progression are related to certain inflammatory indicators. Neutrophils are the paramount cells in causing inflammatory response during acute phase reactions. Neutrophil/Lymphocytes ratio (N/L) has been associated with the prognosis and mortality of several diseases.

Methods and Materials: The patients and control group in the age range of 18?45 years were included in the study. The relationship between N/L ratio in patients and control group was investigated.

Results: There was a statistically significant difference between the N/L ratios determined during the migraine attacks and the N/L ratio values obtained in the control group. But the non-attacks were not different compared to those of the control group. No statistically significant relationships of N/L ratio were detected with any of the clinical features of migraine, VAS and MIDAS.

Conclusions: The N/L ratio is associated with a migraine attack. However, with N/L ratio, disease duration, attack duration, pain frequency and pain severity; the disease disability cannot be predicted. Keywords : Migraine, neutrophil/lymphocyte ratio, inflammatory pathophysiology