Acıbadem Üniversitesi Sağlık Bilimleri Dergisi 2019 , Vol 10, Issue 4
A Comparison of The Effects of Desflurane and Sevoflurane In Pediatric Adenotonsillectomy Operations
Muharrem Koçyiğit1,Özgen Ilgaz Koçyiğit1,Meltem Güner Can1,Oya Kutlay2
1Acıbadem Universitesi, Anesteziyoloji ve Reanimasyon Anabilim Dalı, İstanbul, Türkiye
2Medicabil Hastanesi, Anesteziyoloji ve Reanimasyon Kliniği, Bursa, Türkiye
DOI : 10.31067/0.2019.170 Objectives: Adenoidectomy and adenotonsillectomy operations are ambulatory (Outpatient) surgeries that are common in pediatric patients. The anesthetics agents which have low blood-tissue-lipid solubility is a good choice for the ambulatory surgery due to rapid induction and emergence. The purpose of this study was to compare the hemodynamic effects and the quality of recovery from desflurane and sevoflurane anesthesia in pediatric patients.

Patients and Methods: Fifty-two ASA physical status I patients, aged between 3-10 that underwent adenoidectomy and adenotonsillectomy were studied. Patients were randomly assigned into two groups: Group D and Group S. After the standard anesthesia induction, 4% desflurane in Group D and 2% sevoflurane in Group S were administered with 40% oxygen ? 60% nitrous oxide for maintenance of anesthesia. Heart rate, Mean arterial pressure and oxygen saturation were recorded before induction, after induction, at intubation, 1., 5., 15., 30. minutes and at the end of the operation and after the extubation. Operation time, anesthesia time and the extubation time were recorded. Patients have stayed in the post-anesthesia care unit for 20 minutes. Modified Aldrete score and the pain-discomfort scale were used to evaluate the quality of emergence from anesthesia.

Results: The demographic data and hemodynamic parameters were similar between the two groups. Extubation time was shorter in the desflurane group (p<0,05). Modified Aldrete scores were higher in Group D (p<0,05) and agitation incidence was higher in Group S in recovery unit (p<0,05).

Conclusion: In pediatric ambulatory patients, compared to sevoflurane, desflurane may be a better choice because of its faster recovery time and the lower incidence of agitation. Keywords : Desflurane, Sevoflurane, agitation, adenoidectomy