Acıbadem Üniversitesi Sağlık Bilimleri Dergisi 2012 , Vol 3, Issue 2
Neuroendocrine Tumors of Unknown Prmary Site: Two Case Reports and Review of The Literature
Mustafa Yıldırım1, Cem Parlak2, Mustafa Yıldız1, Nurullah Bülbüller3, Cem Sezer4, Çetin Kaya1, Dinç Süren4
1Antalya Eğitim ve Araştırma Hastanesi, Tıbbi Onkoloji Bölümü, Antalya, Türkiye
2Antalya Eğitim ve Araştırma Hastanesi, Radyasyon Onkolojisi Kliniği , Antalya, Türkiye
3Antalya Eğitim ve Araştırma Hastanesi, 2. Genel Cerrahi Kliniğ Kliniği , Antalya, Türkiye
4Antalya Eğitim ve Araştırma Hastanesi, Patoloji Kliniği, Antalya, Türkiye
The tumor growing in neuroendocrine cells, which are present in many organs, vary in terms of clinical progress and prognosis. In 13% of these patients, the primary focus of the tumor cannot be identified. Neuroendocrine tumors are characterized by intracytoplasmic neurosecretory granules which are linked to the membrane that can be detected by electron microscopy. Likely to lead to extensive involvement of the lymph node, these tumors can be clinically confused with lymphoproliferative diseases. In this article, we discuss two cases of neuroendocrine tumors presented with extensive involvement of the lymph node of unknown primary, in the light of the existing literature. Keywords : neuroendocrine tumor, cancer of unknown primary, lymphoproliferative